Application
Application| Product Name | 53BP1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to human 53BP1 ( amino terminus )P53-binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double-strand breaks. This also suggests a role in DNA repair, maintaining genomic stability. |
| Immunogen | Synthetic peptide corresponding to the amino-terminus of h53BP1, conjugated to a carrier protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 53BP1 MGC138366 TP53BP1 p202 7158 605230 Q12888 FLJ41424 |
|---|---|
| Target | 53BP1 |
Application
Application| Positive Control | HeLa whole cell lysate |
|---|---|
| Application Notes | For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For long term storage, please keep at -70 °C or below. Avoid repeated freeze-thaw cycles. |
| Storage Buffer | Phosphate-buffered saline, pH 7.2, containing no preservatives |
