Rabbit polyclonal to 5HT7 ReceptorThe neurotransmitter serotonin is thought to play a role in various cognitive and behavioral functions. 5HT7, a serotonin receptor, belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends.5HT7 Receptor has been reported in aorta, brain, heart, placenta, small intestine, spleen, artery, and vessel. An EST has been isolated from a testis library.
Immunogen
Synthetic peptide: YGHLRSFLLPEVGRGL, corresponding to amino acids 13-28 of Rat 5HT7 Receptor.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: Use at a concentration of 1-2 ug/ml. Detects a band of approximately 50 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Protein G
Target Information
Gene Synonyms
5HT 5HT7 receptor Htr7 5Ht7 65032 5 HT7 receptor
Target
5-HT7 receptor
Cellular Localization
Cell Membrane
Application
Application
Western blot analysis of 5-HT7R in A) human brain, B) mouse brain, C) rat brain, and D) human SK-N-SH neuroblastoma cell lysate using at 2 ug/ml.
Positive Control
Tested with human brain tissue lysate.
Application Notes
WB: Use at a concentration of 1-2 ug/ml. Detects a band of approximately 50 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.