Rabbit Polyclonal antibody to A2BP1The Fox-1 family of RNA-binding proteins is evolutionarily conserved, and regulates tissue-specific alternative splicing in metazoa. Fox-1 recognizes a (U)GCAUG stretch in regulated exons or in flanking introns. The protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the product of the SCA2 gene which causes familial neurodegenerative diseases. Fox-1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Immunogen
A synthetic peptide corresponding to a N-terminal region of Human A2BP1
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Cow: 100%; Human: 100%; Mouse: 100%
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
2BP1 RBFOX1 HRNBP1 FOX1 A2BP1
Target
A2BP1
Molecular Weight(MW)
43 KDa (note)
Application
Application
WB analysis of A549 cells using A2BP1 antibody at 1μg/ml.
Application
WB analysis of 293T cells using A2BP1 antibody at 1μg/ml.
Positive Control
293T , A549
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.