Rabbit Polyclonal antibody to ABHD5Comparative Gene Identification-58 (CGI-58) is a causal gene of Dorfman-Chanarin syndrome, a neutral lipid storage disease characterized by the presence of intracellular lipid droplets in tissues. CGI-58 comes from a large family of proteins characterized by an alpha /beta hydrolase fold that activates adipose triglyceride lipase thus, may involve in lipid metabolism.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~45 kDa of CGI-58 in 3T3 cell lysate. Reactivity to other species has not been tested.:
Colocalized with PLIN and ADRP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA.
Application
Application
Western blot analysis of CGI-58 expression in 3T3 cell lysate.
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~45 kDa of CGI-58 in 3T3 cell lysate. Reactivity to other species has not been tested.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.