Application
Western blot analysis of extract from MCF-7, 293, HepG2 cells using ABL1/2 Antibody .Application
Western blot analysis of extract from MCF-7, 293, HepG2 cells using ABL1/2 (Ab-393/439) Antibody| Product Name | ABL1/2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ABL1/2Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks. |
| Immunogen | Peptide sequence around aa.391~395/427~431(D-T-Y-T-A) derived from ABL1/2 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ABL JTK7 bcr/abl c-ABL p150 v-abl ABL1 proto-oncogene tyrosine-protein kinase ABL1 Abelson tyrosine-protein kinase 1 proto-oncogene c-Abl v-abl Abelson murine leukemia viral oncogene homolog 1 c-abl oncogene 1 receptor tyrosine kinase tyrosin |
|---|---|
| Target | ABL1/2 |
| Molecular Weight(MW) | 135, 210 (note) |
Application
Western blot analysis of extract from MCF-7, 293, HepG2 cells using ABL1/2 Antibody .
Application
Western blot analysis of extract from MCF-7, 293, HepG2 cells using ABL1/2 (Ab-393/439) Antibody| Application Notes | Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
