Rabbit Polyclonal antibody to ACADMThis gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human ACADM
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MCADH MCAD ACAD1 acyl-CoA dehydrogenase C-4 to C-12 straight chain
Target
ACADM
Molecular Weight(MW)
47 kDa (note)
Application
Application
Western blot analysis of extracts of HepG2 cell line, using ACADM antibody.
Application
Immunohistochemistry of paraffin-embedded mouse kidney using ACADM antibody at dilution of 1:200 (x400 lens)