Application
Western blot analysis of ACC1 phosphorylation expression in Insulin treated K562 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.| Product Name | Acetyl-CoA Carboxylase 1 (phospho Ser80) antibody |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Acetyl-CoA Carboxylase 1 (phospho Ser80)Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide derived from human Acetyl-CoA Carboxylase 1 around the phosphorylation site of Ser80 |
| Modification | p-Ser80 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| WB 1:500-1:2000, IHC 1:50-1:200: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ACACA ACC1 (phospho Ser80) (phospho Ser80) Phospho ACC1 (phospho Ser80) S80 ACC1 (phospho Ser80) Phospho phospho ACC1 (phospho Ser80) (pS80) Phospho ACC1 (phospho Ser80) phospho ACC1 (phospho Ser |
|---|---|
| Target | Acetyl-CoA Carboxylase 1 (phospho Ser80) |
| Tissue Specificity | ACACA |
Application
Western blot analysis of ACC1 phosphorylation expression in Insulin treated K562 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.| Application Notes | WB 1:500-1:2000, IHC 1:50-1:200: |
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
