Rabbit Polyclonal antibody to AChR gamma (cholinergic receptor, nicotinic, gamma)For background information on the acetylcholine receptor (AChR), see CHRNA1 (MIM 100690). Two forms of AChR are found in mammalian skeletal muscle cells. The mature form is predominant in innervated adult muscle and the embryonic form is present in fetal and denervated muscle. Embryonic and mature AChR differ by the replacement of the gamma subunit in the pentameric glycoprotein complex by its isoform, the epsilon subunit (MIM 100725), which is specific to the mature AChR subtype. This switch is mediated by ARIA (acetylcholine receptor-inducing activity; MIM 142445).[supplied by OMIM]
Immunogen
Recombinant protein encompassing a sequence within the center region of human AChR gamma. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
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Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (83%), Rat (83%), Bovine (89%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)