Rabbit Polyclonal antibody to ACOX1The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human ACOX1
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:100 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
acyl-CoA oxidase 1 palmitoyl SCOX PALMCOX ACOX
Target
ACOX1
Application
Application
Western blot analysis of extract of various cells, using ACOX1 antibody.
Application
Immunohistochemistry of paraffin-embedded mouse brain using ACOX1 antibody at dilution of 1:100 (40x lens).