Rabbit Polyclonal antibody to ADAMTS18 (ADAM metallopeptidase with thrombospondin type 1 motif, 18)This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human ADAMTS18. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (87%), Rat (87%), Bovine (91%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
ADAMTS21 antibody ADAMTS18 antibody A disintegrin and metalloproteinase with thrombospondin motifs 18 antibody "a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 21 antibody" disintegrin and metalloprotease-like
Molecular Weight(MW)
135 kDa (note) (2)
Cellular Localization
Secreted , extracellular space , extracellular matrix
Application
Application
Sample (30 ug of whole cell lysate) A: NT2D1 5% SDS PAGE diluted at 1:500
Positive Control
NT2D1
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.