Rabbit Polyclonal antibody to ALDH1A2This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
Immunogen
Recombinant protein of human ALDH1A2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
aldehyde dehydrogenase 1 family member A2 RALDH2T RALDH2 RALDH(II)
Target
ALDH1A2
Application
Application
Western blot analysis of extracts of various cell lines, using ALDH1A2 antibody.
Application
Immunohistochemistry of paraffin-embedded rat kidney using ALDH1A2 antibody at dilution of 1:100 (x400 lens).