Application
Immunohistochemical analysis of frozen bovine cornea section, using ALDH3A1 antibody at 1:100 dilution.| Product Name | ALDH3A1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to aldehyde dehydrogenase 3A1 (aldehyde dehydrogenase 3 family, memberA1)Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human aldehyde dehydrogenase 3A1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-F |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Bovine |
| Predicted Reactivity | Human, Mouse, Rat, DogHuman (100%), Mouse (82%), Rat (83%), Dog (91%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ALDH3 antibody ALDHIII antibody MGC10406 antibody ALDH3A1 antibody "aldehyde dehydrogenase dimeric NADP-preferring antibody" stomach aldehyde dehydrogenase antibody aldehyde dehydrogenase type III antibody aldehyde dehydrogenase isozyme 3 antibody |
|---|---|
| Target | aldehyde dehydrogenase 3A1 |
| Molecular Weight(MW) | 50 kDa (note) (3) |
| Cellular Localization | Cytoplasm |
Application
Immunohistochemical analysis of frozen bovine cornea section, using ALDH3A1 antibody at 1:100 dilution.| Positive Control | Target recombinant protein , *Whole Cornea |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
