Application
Western blot analysis of ALK expression in Jurkat cell lysate (Lane 1 & 2).| Product Name | ALK antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to ALKALK (anaplastic lymphoma kinase) was originally discovered as a NPM (Nucleophosmin)-ALK fusion protein. The NPM-ALK is a constitutively active oncogenic tyrosine kinase associated with anaplastic lymphoma. Activation of PLCgamma by NPM-ALK has been suggested as a crucial step for this lymphoma-associated oncogenic tyrosine kinase. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects human ALK (~200 kDa) and NPM-ALK (~80 kDa).: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ALK Anaplastic lymphoma kinase CD 246 CD246 ALK tyrosine kinase receptor |
|---|---|
| Target | ALK |
| Tissue Specificity | This antibody is specific for ALK. |
Application
Western blot analysis of ALK expression in Jurkat cell lysate (Lane 1 & 2).| Application Notes | Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects human ALK (~200 kDa) and NPM-ALK (~80 kDa).: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
