| Product Name | alpha 2 Catenin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to alpha 2 CateninThe catenins (alpha, beta, and gamma) are cytoplasmic proteins found in varying abundance in many developing and adult tissues. Catenins bind directly or indirectly to the conserved cytoplasmic tail domain of the cell adhesion cadherins. The association of catenins to cadherins produces a complex, which is linked to the actin filament network. Catenins/cadherin complexes play an important role in mediating cell adhesion, transduction of cell-cell contact positional signals to the cell interior, and may play a crucial role in cell differentiation. Alpha-Catenin (CAP102, 102 kDa), originally described as an E-cadherin associated protein, has been shown to associate with other members of the cadherin family members, N-cadherin and P-cadherin. |
| Immunogen | Synthetic peptide: DLANRFKEFGKKMVKL conjugated to KLH, corresponding to amino acids 171-186 of Human alpha 2 Catenin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a dilution of 1/1000. Detects a band of approximately 102 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
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| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Gene Synonyms | CAPR alpha2 Catenin CTNNA2 114025 CAP-R P26232 1496 alpha 2 Catenin CTNR CAP R alpha catenin antibody alpha catenin |
|---|---|
| Target | alpha 2 Catenin |
| Tissue Specificity | Anti-alpha-N-Catenin recognizes alpha-N-catenin (102 kDa) by immunoblotting.Staining of the alpha-N-catenin band in immunoblotting is specifically inhibited with the alpha-N-catenin immunizing peptide (human, amino acids 171-186). |
| Application Notes | WB: Use at a dilution of 1/1000. Detects a band of approximately 102 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 15mM Sodium Azide; Constituents: 0.01M PBS. pH 7.4 |
