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alpha Actinin 1 antibody

Catalog Number:OM239036
OM239036
Discount Price
OM239036-100ul
1~2 Week
100ul
OM239036-50ul
50ul
OM239036-20ul
20ul
1~2 Week
Product Profile
Product Name alpha Actinin 1 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to alpha Actinin 1Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human ACTN1
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCIHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Species Reactivity HumanMouseMonkeyRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms actinin alpha 1
ACTN1
Target alpha Actinin 1
Application

Application

Western blot analysis of extracts of various cell lines using ACTN1 antibody.

Application

Immunohistochemistry of paraffin-embedded mouse heart using ACTN1 antibody at dilution of 1:100 (400x lens).

Application

Immunohistochemistry of paraffin-embedded human esophageal using ACTN1 antibody at dilution of 1:100 (400x lens).

Application

Immunohistochemistry of paraffin-embedded human liver cancer using ACTN1 antibody at dilution of 1:100 (400x lens).

Application

Immunohistochemistry of paraffin-embedded human lung cancer using ACTN1 antibody at dilution of 1:100 (400x lens).
Application Notes WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Additional Information
Form Liquid
Storage Instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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