Rabbit polyclonal antibody to alpha ElastinThis gene encodes a protein that is one of the two components of elastic fibers. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen
Human alpha elastin.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-P
IHC-P:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanBovineShrew
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
SVAS ELN WS WBS
Target
Alpha Elastin
Tissue Specificity
This antibody recognizes alpha and beta human Elastin. It is also known to cross react with bovine alpha Elastin.
Application Notes
IHC-P:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.