Rabbit polyclonal antibody to ALS (insulin-like growth factor binding protein, acid labile subunit)The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human ALS. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
PigPig (85%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ALS antibody IGFALS antibody insulin-like growth factor binding protein complex acid labile chain antibody insulin-like growth factor-binding protein complex acid labile subunit antibody "insulin-like growth factor binding protein acid labile subunit
Target
ALS
Molecular Weight(MW)
66 kDa (note) (2)
Cellular Localization
Secreted , extracellular space
Application
Application
Sample (30 ug of whole cell lysate) A: H1299 B: Hela 7.5% SDS PAGE diluted at 1:1000