Rabbit Polyclonal antibody to ALS (insulin-like growth factor binding protein, acid labile subunit)The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human ALS. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Pig, BovinePig (84%), Bovine (80%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
ALS antibody IGFALS antibody insulin-like growth factor binding protein complex acid labile chain antibody insulin-like growth factor-binding protein complex acid labile subunit antibody "insulin-like growth factor binding protein acid labile subunit
Molecular Weight(MW)
66 kDa (note) (2)
Cellular Localization
Secreted , extracellular space
Application
Application
Sample (30 ug of whole cell lysate) A: THP-1 7.5% SDS PAGE diluted at 1:1000
Application
Immunohistochemical analysis of paraffin-embedded human hepatoma, using ALS antibody at 1:500 dilution.
Positive Control
THP-1
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.