Rabbit polyclonal antibody to Aquaporin 3Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
Immunogen
Synthetic peptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAWB
We recommend the following starting dilutions: For ELISA: Use at a dilution of 1:10000. For WB: Use at a dilution of 1:500. Optimal working dilutions should be determined experimentally be the end user.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
GIL
Target
Aquaporin 3
Application
Application
Western blot of AQP3 using antibody 1:500 in diluObuffer. MW of AQP3 32kDa.
Application Notes
We recommend the following starting dilutions: For ELISA: Use at a dilution of 1:10000. For WB: Use at a dilution of 1:500. Optimal working dilutions should be determined experimentally be the end user.
Additional Information
Form
Liquid
Storage Instructions
Product should be aliquoted and stored at -20∞C. Avoid repeated freeze/thaw cycles.