Application
Western blot analysis of anti-CYP19A1 Pab in Jurkat cell line lysates (35ug/lane).CYP19A1 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human placenta tissue reacted with CYP19A1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | Aromatase antibody, C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Aromatase (CYP19A1) (C-term)This gene encodes a member of the cytochrome P45 superfamily of enzymes. The cytochrome P45 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq] |
| Immunogen | KLH conjugated synthetic peptide between 461~491 amino acids from the C-terminal region of human CYP19A1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| ELISA: Use at 1:1,000: |
|
| Species Reactivity | Human |
| Concentration | 0.2mg/ml |
| Gene Synonyms | CYPXIX P-450AROM Cytochrome P450 19A1 P450AROM CYP19A1 Aromatase Cytochrome P45019A1 Estrogen synthetase P 450AROM |
|---|---|
| Target | Aromatase (CYP19A1) |
| Molecular Weight(MW) | 57.883 kDa (note) |
Application
Western blot analysis of anti-CYP19A1 Pab in Jurkat cell line lysates (35ug/lane).CYP19A1 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human placenta tissue reacted with CYP19A1 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | ELISA: Use at 1:1,000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.09% (W/V) sodium azide |
