Rabbit polyclonal antibody to ASPP2 (tumor protein p53 binding protein, 2)This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human ASPP2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
53BP2 antibody ASPP2 antibody BBP antibody P53BP2 antibody PPP1R13A antibody TP53BP2 antibody "apoptosis-stimulating protein of p53 2 antibody" tumor suppressor p53-binding protein 2 antibody renal carcinoma antigen NY-REN-51 antibody apoptosis-s
Target
ASPP2
Molecular Weight(MW)
126 kDa (note) (2)
Cellular Localization
Cytoplasm , perinuclear region , Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE diluted at 1:1000
Positive Control
NT2D1
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.