Application
Western blot analysis of ATM (pS1981) expression in Hela (A); Raw264.7 (B); H9C2 (C) whole cell lysates.| Product Name | ATM (phospho Ser1981) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ATM (phospho Ser1981)The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ATM (pS1981). The exact sequence is proprietary. |
| Modification | p-Ser1981 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | TEL1 TELO1 ATA ATM ATDC ATM serine/threonine kinase ATC ATD AT1 ATE |
|---|---|
| Target | ATM (phospho Ser1981) |
| Tissue Specificity | Recognizes endogenous levels of ATM (pS1981) protein. |
Application
Western blot analysis of ATM (pS1981) expression in Hela (A); Raw264.7 (B); H9C2 (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
