| Product Name | ATP7A antibody , N-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ATP7A (ATPase, Cu++ transporting, alpha polypeptide)This gene encodes a transmembrane protein that functions in copper transport across membranes. The protein localizes to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. The protein relocalizes to the plasma membrane under conditions of elevated extracellular copper and functions in the efflux of copper from cells. Mutations in this gene result in Menkes disease, X-linked cutis laxa, and occipital horn syndrome. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human ATP7A. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, BovineHuman (100%), Mouse (82%), Bovine (87%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DSMAX antibody FLJ17790 antibody MK antibody MNK antibody SMAX3 antibody ATP7A antibody Menkes disease-associated protein antibody Cu++-transporting P-type ATPase antibody copper pump 1 antibody copper-transporting ATPase 1 antibody "ATPase Cu++ |
|---|---|
| Molecular Weight(MW) | 163 kDa (note) |
| Cellular Localization | Golgi apparatus , trans-Golgi network membrane , Cell membrane , Isoform 3: Cytoplasm , cytosol , Isoform 5: Endoplasmic reticulum |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
