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AXL antibody

Catalog Number:OM240833
OM240833
Discount Price
OM240833-100ul
1~2 Week
100ul
OM240833-50ul
50ul
OM240833-20ul
20ul
1~2 Week
Product Profile
Product Name AXL antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to AXL (AXL receptor tyrosine kinase)The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human AXL. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity HumanRat
Predicted Reactivity Mouse, PigMouse (85%), Pig (81%)
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms AXL receptor tyrosine kinase
JTK11
UFO
Target AXL
Molecular Weight(MW) 98 kDa (note) (2)
Cellular Localization Membrane; Single-pass type I membrane protein
Application

Application

AXL antibody detects AXL protein at cell membrane and cytoplasm in rat prostate by immunohistochemical analysis. Sample: Paraffin-embedded rat prostate. AXL antibody diluted at 1:1000.

Application

AXL antibody detects AXL protein by western blot analysis. A. 30 μg 293T whole cell lysate/extract B. 30 μg whole cell lysate/extract of human AXL-transfected 293T cells 7.5 % SDS-PAGE AXL antibody dilution: 1:5000
Positive Control human AXL-transfected 293T
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
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