Rabbit polyclonal antibody to BAKThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Immunogen
A peptide corresponding to 13 amino acids near the amino terminus of human BAK.
This antibody recognizes the Bcl-2 homologous antagonist/killer (Bak).
Application
Application
WB analysis of L1210 cell lysate using BAK antibody at (A) 1 and (B) 2 ug/ml.
Application Notes
Immunohistology - Frozen: Max Dilution 2 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.