Application
Immunofluorescence of Bfl-1 in Mouse Kidney tissue with Bfl-1 antibody at 20 ug/mL.Application
Western blot analysis of Bfl-1 in human kidney tissue lysate with Bfl-1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.Application
Immunohistochemistry of Bfl-1 in mouse kidney tissue with Bfl-1 antibody at 10 ug/mL.| Product Name | BCL2A1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to BCL2A1This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | Bfl-1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Bfl-1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| WB: 0.5 - 2 ug/ml. IHC-P: 10 ug/ml. IF: 20 ug/ml: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | BCL2L5 ACC-2 ACC-1 ACC1 GRS BCL2-related protein A1 BFL1 HBPA1 ACC2 |
|---|---|
| Target | BCL2A1 |
| Tissue Specificity | At least two isoforms of Bfl-1 are known to exist; this antibody will only detect the larger isoform. |
Application
Immunofluorescence of Bfl-1 in Mouse Kidney tissue with Bfl-1 antibody at 20 ug/mL.
Application
Western blot analysis of Bfl-1 in human kidney tissue lysate with Bfl-1 antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.
Application
Immunohistochemistry of Bfl-1 in mouse kidney tissue with Bfl-1 antibody at 10 ug/mL.| Application Notes | WB: 0.5 - 2 ug/ml. IHC-P: 10 ug/ml. IF: 20 ug/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
