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BCL2L10 antibody

Catalog Number:OM241183
OM241183
Discount Price
OM241183-100ul
1~2 Week
100ul
OM241183-50ul
50ul
OM241183-20ul
20ul
1~2 Week
Product Profile
Product Name BCL2L10 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to BCL2L10The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008]
Immunogen Bcl-B antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human Bcl-B.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAICC/IFWB
WB: 1 ug/ml. ICC: 10 ug/ml:
Species Reactivity Human
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms Boo
Diva
BCL2-like 10 (apoptosis facilitator)
BCL-B
Target BCL2L10
Application

Application

Immunocytochemistry of Bcl-B in Jurkat cells with Bcl-B antibody at 10 ug/mL.

Application

Western blot analysis of Bcl-B in Jurkat lysate with Bcl-B antibody at 1 ug/ml in the (A) absence and (B) presence of blocking peptide.
Application Notes WB: 1 ug/ml. ICC: 10 ug/ml:
Additional Information
Form Liquid
Storage Instructions Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer PBS containing 0.02% sodium azide.
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