Rabbit polyclonal antibody to Bcl-w (BCL2-like 2)This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human Bcl-w. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
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Predicted Reactivity
Human, Mouse, Rat, Dog, BovineHuman (100%), Mouse (99%), Rat (99%), Dog (100%), Bovine (100%)