Rabbit polyclonal antibody to BEST3BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD; MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738]; Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM]
Immunogen
Internal cytoplasmic domain of human.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHC-P
IHC-P (5 µg/ml):
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
MGC13168 MGC40411 VMD2L3
Tissue Specificity
Human BEST3
Application
Application
Immunohistochemical staining of human Testis tissue sections using BEST3 antibody
Application
Immunohistochemical staining of human Colon tissue sections using BEST3 antibody