Application
Western blot analysis of Beta-2 Adrenergic Receptor (pS346) expression in HepG2 PMA-treated (A); mouse spleen (B); rat spleen (C) whole cell lysates.| Product Name | beta 2 Adrenergic receptor (phospho Ser346) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to beta 2 Adrenergic receptor (phospho Ser346)This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Beta-2 Adrenergic Receptor. The exact sequence is proprietary. |
| Modification | p-Ser346 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ADRBR ADRB2R adrenoceptor beta 2 surface BAR BETA2AR B2AR ADRB2 |
|---|---|
| Target | beta 2 Adrenergic receptor |
| Tissue Specificity | Recognizes endogenous levels of Beta-2 Adrenergic Receptor (pS346) protein. |
Application
Western blot analysis of Beta-2 Adrenergic Receptor (pS346) expression in HepG2 PMA-treated (A); mouse spleen (B); rat spleen (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
