Application
Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | beta 2 Adrenergic Receptor (phospho Ser346) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to beta 2 Adrenergic Receptor (phospho Ser346)This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008] |
| Immunogen | Peptide sequence around phosphorylation site of serine 346 (R-S-S(p)-L-K) derived from Human Adrenergic Receptor beta2. |
| Modification | p-Ser346 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ADRB2 adrenoceptor beta 2 surface B2AR BAR ADRBR ADRB2R BETA2AR |
|---|---|
| Target | beta 2 Adrenergic Receptor (phospho Ser346) |
| Tissue Specificity | The antibody detects endogenous level of Adrenergic Receptor beta2 only when phosphorylated at serine 346. |
Application
Western blot analysis of extracts from HepG2 cells treated with Nocodazole using Phospho-Adrenergic Receptor beta2 (Ser346) antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
