Application
Western blot analysis of BMX (pY40) expression in MCF7 IL1b-treated (A); Jurkat CD3-treated (B); Raw264.7 IL1b-treated (C); H9C2 IL1b-treated (D) whole cell lysates.| Product Name | BMX (phospho Tyr40) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to BMX (phospho Tyr40)This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human BMX. The exact sequence is proprietary. |
| Modification | p-Tyr40 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BMX ETK PSCTK3 PSCTK2 BMX non-receptor tyrosine kinase |
|---|---|
| Target | BMX(phospho Tyr40) |
| Tissue Specificity | Recognizes endogenous levels of BMX (pY40) protein. |
Application
Western blot analysis of BMX (pY40) expression in MCF7 IL1b-treated (A); Jurkat CD3-treated (B); Raw264.7 IL1b-treated (C); H9C2 IL1b-treated (D) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
