Application
Sample (30μg whole cell lysate) A:HeLa S3 10% SDS PAGE diluted at 1:500Application
BPNT1 antibody [N1C3] detects BPNT1 protein at cytosol on mouse pancreas by immunohistochemical analysis. Sample: Paraffin-embedded mouse pancreas. BPNT1 antibody [N1C3] dilution: 1:500.Application
Sample (50 ug of whole cell lysate) A: Mouse liver 12% SDS PAGE diluted at 1:1000Application
BPNT1 antibody [N1C3] detects BPNT1 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. BPNT1 antibody [N1C3] dilution: 1:500.| Product Name | BPNT1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1)BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human BPNT1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, Xenopus laevis, Chicken, BovineRat (94%), Xenopus laevis (84%), Chicken (83%), Bovine (93%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PIP antibody BPNT1 antibody bisphosphate 3'-nucleotidase 1 antibody BPntase antibody "PAP-inositol-1 4-phosphatase antibody" "3'(2') 5'-bisphosphate nucleotidase 1 antibody" "3'(2') 5'-bisphosphate nucleotidase 1 antibody" |
|---|---|
| Molecular Weight(MW) | 33 kDa (note) (3) |
Application
Sample (30μg whole cell lysate) A:HeLa S3 10% SDS PAGE diluted at 1:500
Application
BPNT1 antibody [N1C3] detects BPNT1 protein at cytosol on mouse pancreas by immunohistochemical analysis. Sample: Paraffin-embedded mouse pancreas. BPNT1 antibody [N1C3] dilution: 1:500.
Application
Sample (50 ug of whole cell lysate) A: Mouse liver 12% SDS PAGE diluted at 1:1000
Application
BPNT1 antibody [N1C3] detects BPNT1 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. BPNT1 antibody [N1C3] dilution: 1:500.| Positive Control | HeLaS3 , mouse liver |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
