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C4 binding protein B antibody

Catalog Number:OM242505
OM242505
Discount Price
OM242505-100ul
1~2 Week
100ul
OM242505-50ul
50ul
OM242505-20ul
20ul
1~2 Week
Product Profile
Product Name C4 binding protein B antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to C4 binding protein B (complement component 4 binding protein, beta)This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human C4 binding protein B. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity HumanMouse
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms C4BP antibody
C4BPB antibody
C4b-binding protein beta chain antibody
"complement component 4 binding protein
beta antibody"
Molecular Weight(MW) 28 kDa (note) (5)
Cellular Localization Secreted
Application

Application

Sample (30 ug of whole cell lysate) A: BCL-1 12% SDS PAGE diluted at 1:1000

Application

Immunohistochemical analysis of paraffin-embedded human hepatoma, using C4 binding protein B antibody at 1:500 dilution.

Application

Sample (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 12% SDS PAGE diluted at 1:1000
Positive Control Jurkat , Raji , K562 , BCL-1
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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