| Product Name | c-Abl antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal to c-AblThe c-Abl proto-oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c-Abl proto-oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (The Philadelphia Chromosome) as the result of the fusion of c-Abl sequences from Chromosome 9 to the Bcr gene on Chromosome 22. c-Abl reacts with c-Abl p120 and chimeric Bcr/Abl proteins. |
| Immunogen | A synthetic peptide derived from the sequence adjacent to protein tyrosine kinase domain of human and mouse c-Abl protein. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| For IHC-P: Use at a dilution of 1:4000. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | JTK7 ABL1 vabl P00519 ABL 25 cABL p150 v-abl 189980 c-ABL c Abl v abl |
|---|---|
| Target | c-Abl |
| Cellular Localization | Cytoplasmic and Nuclear |
| Positive Control | HeLa cells, Placenta |
|---|---|
| Application Notes | For IHC-P: Use at a dilution of 1:4000. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM Phosphate-buffered saline, pH 7.4 containing 0.2% BSA & 0.1% sodium azide |
