Application
Immunohistochemistry of CAPS1 in human brain with CAPS1 antibody at 5 ug/ml.Application
Western blot analysis of CAPS1 in rat brain tissue lysate with CAPS1 antibody at (A) 0.25 and (B) 0.5 ug/ml.| Product Name | CAPS1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CAPS1CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CADPS1 Calcium-dependent secretion activator 1 Calciumdependent secretion activator 1 CAPS CAPS1 Calciumdependent secretion activator1 |
|---|---|
| Target | CAPS1 |
| Tissue Specificity | This antibody is specific for CAPS1 |
Application
Immunohistochemistry of CAPS1 in human brain with CAPS1 antibody at 5 ug/ml.
Application
Western blot analysis of CAPS1 in rat brain tissue lysate with CAPS1 antibody at (A) 0.25 and (B) 0.5 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85036-PEP - CAPS1 Peptide Lysates: Cat. No. GTX27942 - Rat Brain Tissue Lysate |
|---|---|
| Application Notes | IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
