Rabbit polyclonal antibody to Carboxypeptidase EThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. [provided by RefSeq, Jul 2008]
Immunogen
Synthetic peptide derived from the C-terminus of carboxypeptidase H conjugated to KLH
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHC-FIPWB
Immunohistology - Frozen: 1/100 - 1/200:
Species Reactivity
HumanMouseMonkeyRatBovine
Concentration
1mg/ml
Purification
Serum
Target Information
Gene Synonyms
carboxypeptidase E CPE
Target
Carboxypeptidase H
Tissue Specificity
This antibody recognizes carboxypeptidase H also known as carboxypeptidase E.
Application Notes
Immunohistology - Frozen: 1/100 - 1/200:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.