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Caspase 10 antibody

Catalog Number:OM243264
OM243264
Discount Price
OM243264-100ul
1~2 Week
100ul
OM243264-50ul
50ul
OM243264-20ul
20ul
1~2 Week
Product Profile
Product Name Caspase 10 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to Caspase 10 (caspase 10, apoptosis-related cysteine peptidase)This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human Caspase 10. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity Human
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms ALPS2 antibody
FLICE2 antibody
MCH4 antibody
CASP10 antibody
interleukin-1B-converting enzyme 2 antibody
FAS-associated death domain protein interleukin-1B-converting enzyme 2 antibody
CASP-10 antibody
"caspase 10
apoptosis-related cysteine proteas
Molecular Weight(MW) 59 kDa (note) (3)
Application

Application

Immunofluorescence analysis of methanol-fixed HeLa, using Caspase 10 antibody at 1:500 dilution.

Application

Caspase 10 antibody detects Caspase 10 protein at cytoplasm in human lung cancer by immunohistochemical analysis. Sample: Paraffin-embedded human lung cancer. Caspase 10 antibody diluted at 1:500.

Application

Sample (30 ug of whole cell lysate) A: Jurkat B: NCI-H929 7.5% SDS PAGE diluted at 1:1000

Application

Immunohistochemical analysis of paraffin-embedded U87 xenograft, using Caspase 10 antibody at 1:500 dilution.
Positive Control Jurkat , NCI-H929
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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