Application
Western blot analysis of extracts from Jurkat cells, treated with Etoposide 25uM 24h, using Caspase 7 (Cleaved-Asp198) antibody . The lane on the right is treated with the synthesized peptide.Application
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 7 (Cleaved-Asp198) antibody . The picture on the right is treated with the synthesized peptide.| Product Name | Caspase 7 (cleaved Asp198) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Caspase 7 (cleaved Asp198)Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 7. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIHC-PWB |
| IHC: 1:50~1:100 : |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ICELAP3Apoptotic protease Mch3 Caspase EC 3.4.22. CASP-7 ICElike apoptotic protease3 EC 3.4.22. CASP7 EC3.4.22. CASP7 ICElike apoptotic protease 3 MCH3 Caspase-7 [Precursor] ICE-LAP3Apoptotic protease Mch-3 CMH-1 CASP7 Caspase7 [Precursor] CMH |
|---|---|
| Target | Caspase 7 |
| Molecular Weight(MW) | 20 kDa (note) |
| Tissue Specificity | Caspase 7 (Cleaved-Asp198) Antibody detects endogenous levels of fragment of activated Caspase 7 resulting from cleavage adjacent to Asp198. |
Application
Western blot analysis of extracts from Jurkat cells, treated with Etoposide 25uM 24h, using Caspase 7 (Cleaved-Asp198) antibody . The lane on the right is treated with the synthesized peptide.
Application
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 7 (Cleaved-Asp198) antibody . The picture on the right is treated with the synthesized peptide.| Application Notes | IHC: 1:50~1:100 : |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
