| Product Name | Caspase 7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal to Caspase 7 ( Mch 3 )Caspase 7 functions as an effector caspase that cleaves downstream substrates responsible for producing the morphological and biochemical changes associated with apoptosis. The alpha form of Caspase 7 is 303 amino acids and gets cleaved upon activation to 20 and 12 kD subunits. A 253 aa b form, presumably a result of alternative splicing, lacks the cysteine protease active site (QACRG) and may function as a dominant negative regulator of apoptosis. |
| Immunogen | Recombinant full length Human Caspase 7 protein |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ICELAP3 ICE-LAP3 CMH-1 CASP7 CMH1 601761 Caspase 7 840 Caspase7 P55210 MCH3 CMH 1 ICE LAP3 |
|---|---|
| Target | Caspase 7 |
| Cellular Localization | Cytoplasmic |
| Positive Control | Jurkat Cells |
|---|---|
| Application Notes | For WB: Use at a dilution of 1:500. Optimal dilutions/concentrations should be determined by the researcher.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | 10mM Phosphate-buffered saline containing 0.2% BSA and 0.1% sodium azide |
