Application
Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE diluted at 1:1000| Product Name | Caspase 7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Caspase 7 (caspase 7, apoptosis-related cysteine peptidase)This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Caspase 7. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, RatMouse (83%), Rat (87%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CMH-1 antibody ICE-LAP3 antibody MCH3 antibody CASP7 antibody "caspase 7 apoptosis-related cysteine protease antibody" CASP-7 antibody Lice2 alpha/beta/gamma antibody caspase 7 isoform delta antibody apoptotic protease MCH-3 antibody caspase-7 an |
|---|---|
| Molecular Weight(MW) | 34 kDa (note) (4) |
| Cellular Localization | Cytoplasm |
Application
Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE diluted at 1:1000| Positive Control | 293T , A431 , Jurkat , Raji |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
