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Cathepsin B antibody

Catalog Number:OM243408
OM243408
Discount Price
OM243408-100ul
1~2 Week
100ul
OM243408-50ul
50ul
OM243408-20ul
20ul
1~2 Week
Product Profile
Product Name Cathepsin B antibody
Antibody Type Primary Antibodies
Product description Rabbit monoclonal antibody [EPR4323] to Cathepsin BThe protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Key Feature
Clonality Monoclonal
Isotype IgG
Clone Number EPR4323
Host Species Rabbit
Tested Applications ICC/IFIHC-PIPWB
IP: use at a dilution of 1:10 - 1:100.:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms CPSB
cathepsin B
CTSB
APPS
Target Cathepsin B
Molecular Weight(MW) 38 kDa (note)
Application

Application

ICC/IF analysis of HeLa cells using Cathepsin B antibody [EPR4323] at a dilution of 1:50 (red) and DAPI (blue).

Application

IHC-P analysis of human kidney tissue using Cathepsin B antibody [EPR4323] at a dilution of 1:50.

Application

IHC-P analysis of human papillary carcinoma tissue using Cathepsin B antibody [EPR4323] at a dilution of 1:50.

Application

WB analysis of (1) HT1080, (2) A375, (3) SW480 and (4) A549 lysates (10 μg per lane) using Cathepsin B antibody [EPR4323] at a dilution of 1:1,000.
Application Notes IP: use at a dilution of 1:10 - 1:100.:
Additional Information
Form Liquid
Storage Instructions Stable for 12 months at -20°C.
Storage Buffer PBS containing 50% Glycerol, 0.05% BSA and 0.01% Sodium azide.
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