Application
IHC-P analysis of human lung tissue using Caveolin 1 antibody [E249].Application
IHC analysis of developing human lung tissue using Caveolin 1 antibody [E249] at a dilution of 1:250.Application
WB analysis of A431 lysate using Caveolin 1 antibody [E249].| Product Name | Caveolin 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit monoclonal antibody [E249] to Caveolin 1The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010] |
| Immunogen | Synthetic peptide corresponding to human Caveolin-1 aa 150-250. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Clone Number | E249 |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-PWB |
| ICC/IF:1:200~1:500 IHC:1:50~1:200 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAV1 BSCL3 CGL3 caveolin 1 caveolae protein 22kDa MSTP085 VIP21 |
|---|---|
| Target | Caveolin 1 |
| Tissue Specificity | This antibody should recognize both alpha and beta form of Caveolin-1. |
Application
IHC-P analysis of human lung tissue using Caveolin 1 antibody [E249].
Application
IHC analysis of developing human lung tissue using Caveolin 1 antibody [E249] at a dilution of 1:250.
Application
WB analysis of A431 lysate using Caveolin 1 antibody [E249].| Application Notes | ICC/IF:1:200~1:500 IHC:1:50~1:200 IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Storage Buffer | PBS containing 50% Glycerol, 0.05% BSA and 0.01% Sodium azide. |
