Application
ICC/IF analysis of untreated and 100uM pervanadate-treated HUVEC cells using Caveolin 2 (phospho Tyr19) antibody at a dilution of 1:20 (green). F-actin (red) was stained with a fluorescent red phalloidin and nuclei (blue) were stained with DAPI. Images were taken at a magnification of 60x.| Product Name | Caveolin 2 (phospho Tyr19) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Phospho-Caveolin 2 pTyr19Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types. |
| Immunogen | Synthetic phosphopeptide corresponding to residues M(14) A D D A (pY) S H H S G C(25) of mouse CAV2. |
| Modification | p-Tyr19 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ICC/IFWB |
| ICC/IF: 1:10 - 1:200: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | Caveolin2 Caveolin 2 Cav2 AI447843 CAV P51636 12390 601048 MGC12294 858 Caveolin 2 (phospho Y19) Caveolin 2 (phospho Tyr19) Caveolin 2 (pY19) Caveolin 2 (pTyr19) Caveolin 2 phospho Y19 Caveolin 2 phospho Tyr19 Phospho Caveolin 2 (Y19) Phos |
|---|---|
| Target | Phospho-Caveolin 2 pTyr19 |
Application
ICC/IF analysis of untreated and 100uM pervanadate-treated HUVEC cells using Caveolin 2 (phospho Tyr19) antibody at a dilution of 1:20 (green). F-actin (red) was stained with a fluorescent red phalloidin and nuclei (blue) were stained with DAPI. Images were taken at a magnification of 60x.| Application Notes | ICC/IF: 1:10 - 1:200: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 1 mg/ml BSA and 0.05% sodium azide. |
