Application
Western blot analysis of CCR5 phosphorylation expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.| Product Name | CCR5 (phospho Ser336) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CCR5 (phospho Ser336)This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gen |
| Immunogen | A synthesized peptide derived from human CCR5 around the phosphorylation site of Ser336 |
| Modification | p-Ser336 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB 1:500-1:2000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | chemokine (C-C motif) receptor 5 (gene/pseudogene) CCR5 CCCKR5 CMKBR5 IDDM22 CCR5 (phospho Ser336) Phospho S336 CCR5 (phospho Ser336) (pS336) phospho CCR5 (phospho Ser336) (Ser336) Anti |
|---|---|
| Target | CCR5 (phospho Ser336) |
| Tissue Specificity | CCR5 |
Application
Western blot analysis of CCR5 phosphorylation expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide.| Application Notes | WB 1:500-1:2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
