Rabbit monoclonal antibody [EPR3693] to CD2CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
Immunogen
Synthetic peptide corresponding to residues in human CD2.
Key Feature
Clonality
Monoclonal
Isotype
IgG
Clone Number
EPR3693
Host Species
Rabbit
Tested Applications
ICC/IFWB
ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
LFA-2 CD2 molecule SRBC T11
Target
CD2
Application
Application
WB analysis of (1) PBMC and (2) Jurkat lysates (10 μg per lane) using CD2 antibody [EPR3693] at a dilution of 1:1,000.
Application Notes
ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.