Application
Sample (30 ug of whole cell lysate) A: K562 12% SDS PAGE diluted at 1:1000| Product Name | CD3 epsilon antibody , C-term |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CD3E (CD3E molecule, epsilon (CD3-TCR complex))The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq] |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human CD3 epsilon. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cat, Pig, Rabbit, Sheep, BovineMouse (87%), Rat (87%), Dog (87%), Cat (87%), Pig (100%), Rabbit (93%), Sheep (87%), Bovine (80%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FLJ18683 antibody T3E antibody TCRE antibody CD3E antibody "T-cell antigen receptor complex epsilon subunit of T3 antibody" CD3-epsilon antibody "CD3e antigen epsilon polypeptide (TiT3 complex) antibody" T-cell surface antigen T3/Leu-4 epsilon cha |
|---|---|
| Molecular Weight(MW) | 23 kDa (note) |
| Cellular Localization | Membrane |
Application
Sample (30 ug of whole cell lysate) A: K562 12% SDS PAGE diluted at 1:1000| Positive Control | K562 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
