Rabbit polyclonal antibody to CD30The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml):
Species Reactivity
Rat
Predicted Reactivity
Bovine, Horse, Human, Mouse
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Ki-1 TNFRSF8 D1S166E tumor necrosis factor receptor superfamily member 8
Target
CD30
Application
Application
IHC-P analysis of rat brain tissue using CD30 antibody at a dilution of 1:200.
Application
WB analysis of (1) rat brain and (2) rat liver lysates using CD30 antibody at a dilution of 1:200.
Application Notes
P-ELISA:1:500-1000, WB:1:100-500, IHC-P:1:100-500 (based on 0.5 mg/ml):
Additional Information
Form
Liquid
Storage Instructions
Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Storage Buffer
10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide