Application
Western blot analysis of extracts from NIH-3T3 cells treated with PMA using Phospho-CD44 (Ser706) antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | CD44 (phospho Ser706) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CD44 (phospho Ser706)The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008] |
| Immunogen | Peptide sequence around phosphorylation site of serine 706 (S-K-S(p)-Q-E) derived from Human CD44. |
| Modification | p-Ser706 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MIC4 CDW44 HUTCH-I HCELL IN CD44 LHR MDU3 ECMR-III MDU2 CSPG8 CD44 molecule (Indian blood group) Pgp1 MC56 Antib |
|---|---|
| Target | CD44 (phospho Ser706) |
| Tissue Specificity | The antibody detects endogenous level of CD44 only when phosphorylated at serine 706. |
Application
Western blot analysis of extracts from NIH-3T3 cells treated with PMA using Phospho-CD44 (Ser706) antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
