Application
Sample (30 ug of whole cell lysate) A: K562 B: THP-1 7.5% SDS PAGE diluted at 1:500| Product Name | CD68 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to CD68 (macrosialin)This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human CD68. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DKFZp686M18236 antibody GP110 antibody SCARD1 antibody CD68 antibody macrosialin antibody "scavenger receptor class D member 1 antibody" macrophage antigen CD68 antibody CD68 antigen antibody CD68 molecule antibody |
|---|---|
| Molecular Weight(MW) | 37 kDa (note) |
| Cellular Localization | Isoform Short: Cell membrane , Isoform Long: Endosome membrane , Lysosome membrane |
Application
Sample (30 ug of whole cell lysate) A: K562 B: THP-1 7.5% SDS PAGE diluted at 1:500| Positive Control | K562 , THP-1 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
